Friday, August 31, 2012

Toddler Friendly House | Toddler Times

house 300x300 Our Toddler Friendly New HouseWhen we began looking for our new house, I started with a list of the things I disliked about our current house:

-no linen closet
-no mud room
-only 3 bedrooms

? and the things I loved that I wanted to keep:

-formal dining room
-separate living room and play room
-wood flooring
-screened porch

I spoke on here about wondering ?how much space is too much space?? when we started looking at budget and options.? My husband and I decided that we wanted to buy a house that we could grow into for the next 10-20 years with possibly another baby and eventually teenagers. We looked at 10-15 houses in our price range and each had their positives and negatives. We eventually settled on a good deal: a rental that had been vacant, needed some TLC, but had good bones in a good neighborhood with good public schools.? Here?s the other stuff that led it to be ?the one? when we considered our growing family in this house:

  • thumbs 531409 10100361682232951 833873452 n 0 Our Toddler Friendly New House

    Laundry and Mud Room

    Kids are dirty and I see plenty of muddy cleats and boots in my future, so having a drop-zone of a mud room right by the garage was a must-have on my list.

    /toddler-times/2012/08/30/our-toddler-friendly-new-house/#laundry-and-mud-room

  • thumbs 547998 10100361682088241 838455845 n Our Toddler Friendly New House

    A huge bckyard

    For his swingset, soccer ball kicking, playhouse, and room to run with his pup. We are big fans of children playing outside.

    /toddler-times/2012/08/30/our-toddler-friendly-new-house/#a-huge-bckyard

  • thumbs 574908 10100361685511381 1828892539 n Our Toddler Friendly New House

    A separate playroom

    I don't like kids toys and kids mess around me. I know, that's the worst thing a mom can say but I like having separation, so having a place for Harrison's things and then having a place for me to relax in the evening was super important.

    /toddler-times/2012/08/30/our-toddler-friendly-new-house/#a-separate-playroom

  • thumbs 581952 10100361685416571 1157428575 n Our Toddler Friendly New House

    A desk in a common area

    My husband and I decided a long time ago that our children will never have internet access in their rooms or anywhere they can be private. We simply feel that the best monitoring is done when the kid has no idea when you'll pop out and look over his shoulder next. So sure, Harry...you can check email and Facebook. While I make dinner 5 feet away from you.

    /toddler-times/2012/08/30/our-toddler-friendly-new-house/#a-desk-in-a-common-area

  • thumbs bedroom Our Toddler Friendly New House

    Four bedrooms.

    One for us, one for Harry, one guest room...and one for a future baby, maybe.

    /toddler-times/2012/08/30/our-toddler-friendly-new-house/#four-bedrooms

  • thumbs kitchenliving Our Toddler Friendly New House

    Flow

    I like separate rooms, but I also like being able to watch my kid. This means he can play in his playroom while I watch from the kitchen. Win!

    /toddler-times/2012/08/30/our-toddler-friendly-new-house/#flow

More from BA:

Is your toddler eating enough?

Toddler car seat safety. aka SUPER IMPORTANT TO READ.

Yep, you?re that mom.

Beth Anne writes words & takes pictures on The Heir to Blair. You can also find her on the Twitters & Facebook.

 Our Toddler Friendly New House

Source: http://blogs.babble.com/toddler-times/2012/08/30/our-toddler-friendly-new-house/

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2,000 footballers and cheerleaders parade in Dublin ahead of matches

"We're going to rock this Trinity house!" organiser Patrick Steenberger cheered over the tannoy as more than 2,000 American high school footballers and cheerleaders streamed into the quadrangle at Trinity College Dublin last night for an all-American pep rally.

Led by a bagpiper in a blue tartan kilt, a sea of footballers in uniform and bubbly cheerleaders marched to the ear-splitting beat of a bass drum.

They converged in front of the famed Campanile monument to whip up the masses ahead of today's historic clash between nine American and two Canadian high school football teams. It's the first time that these high school football teams have played each other on foreign soil. And even the rainclouds didn't dampen the enthusiasm of the players and their supporters as they paraded from St Stephen's Green.

They are among an estimated 35,000 Americans and Canadians who have been arriving here all week for the event which was organised by the Global Ireland Football Team (GIFT).

The focal point is the sold-out Emerald Isle Classic on Saturday at the Aviva Stadium as part of The Gathering tourism initiative.

Arch rivals Notre Dame University and the US Naval Academy will play the game -- a fixture that dates back to 1927 -- at the start of the American college football season which traditionally takes place on the Labour Day weekend. Not to be outdone by their college counterparts, American high school football teams from Texas to Wisconsin to California will battle it out at Navan's Pairc Tailteann and Dublin's Parnell Park and Donnybrook stadiums today.

Meanwhile, supporters of Notre Dame and Navy will be holding their own pep rallies tonight ahead of tomorrow's 2pm kick-off.

A massive pre-match party will be held for Notre Dame fans at the O2 arena that will be broadcast live on RTE One. Their rivals will also stage a traditional pep rally at St Stephen's Green tonight.

And the party will continue tomorrow with a classic "tailgate party" taking place in Temple Bar from 10am to 1pm. Also tomorrow morning Notre Dame supporters will attend an open-air Mass in Dublin Castle.

Meanwhile, hundreds of US marines and naval crew will be attending the festivities as part of a scheduled stop-over of the USS Fort McHenry which is docked at Dublin Port for the weekend.

Source: http://www.belfasttelegraph.co.uk/news/local-national/republic-of-ireland/2000-footballers-and-cheerleaders-parade-in-dublin-ahead-of-matches-16204777.html?r=RSS

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Zynga hires former online gambling executive Maytal Ginsburg Olsha

Social Casino Intellegence is reporting that Zynga has hired online gambling firm 888?s former senior vice president of corporate and regulated markets Maytal Ginsburg Olsha.

The hire shows that Zynga is gearing up for real-money social gaming overseas, and perhaps here in the U.S. should the company succeed in changing the legislation that currently forbids it. We recently reported that Zynga is spending a lot of cash on lobbying for real-money gaming. The company spent $75,000 in lobbying fees in the last quarter both in Washington and California, centering around a bill that would let companies offer online poker in the state.

Although real-money gaming is still illegal in the United States because of the?Unlawful Internet Gambling Enforcement Act of 2006, it?s very much a part of U.K. culture. As a result, several companies are starting to double down and create social casino games that allow players to gamble with actual cash.

The news also follows casual game developer Big Fish?s announcement two weeks ago that it is joining with Betable to bring real-money gambling to the United Kingdom with Big Fish Casino, a re-branded version of the social mobile casino game Card Ace: Casino. Prior to that announcement, Gamesys launched the first such app on Facebook with Bingo Friendzy.

Source: http://www.insidesocialgames.com/2012/08/31/zynga-hires-former-online-gambling-executive-maytal-ginsburg-olsha/

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Thursday, August 30, 2012

Evolution of mustards' spice: Plants developed chemical defense against bugs, specific to where they live

ScienceDaily (Aug. 30, 2012) ? There's a reason people don't put gobs of mustard on a hot dog. Mustard plants produce a spicy chemical intended to discourage insects from eating them lest they suffer a bad case of heartburn, and it has essentially the same effect on us.

Now, an interdisciplinary and international group of researchers based at Duke University has figured out why some of those wild mustard plants vary as much as they do in terms of that spice. The variation spells the difference between life and death for the plants in the mountainous Rockies where they live, a place where environmental conditions can change quite significantly over relatively short distances.

The study reported in the August 31 issue of the journal Science is one of very few to successfully follow the genes underlying variation of complex traits in a natural setting back to the evolutionary processes that influenced them.

"We were able to put this story together all the way from the plants in the dirt to the amino acids in the laboratory," said Tom Mitchell-Olds, a professor of biology and member of the Duke Institute for Genome Sciences & Policy. "That's where the challenge came in."

Mitchell-Olds' team studies the wild mustard Boechera stricta. Boechera is their organism of choice because its close relationship to the laboratory plant Arabidopsis offers them technical advantages and because the plants live in areas that have been untouched and unchanged for the last 3,000 years.

The researchers first identified a broad region in the plants' genome that was responsible for differences in their chemical defenses, vulnerability to insects and survival and reproduction in nature. "Technically, we had no idea what this would be," Mitchell-Olds said.

Ultimately, they traced those differences back to two amino acid changes in the enzyme controlling the plants' main spicy ingredient. With sophisticated biochemistry, the researchers discovered that this seemingly slight difference alters the spice-building pathway to produce a different defensive chemical -- different in a way that apparently matters quite a lot to insects. When plants carrying the version of that enzyme normally found in Colorado were planted in Montana, they struggled to survive as insects took their toll. When Montana plants were established in Colorado, they too got hammered by bugs.

While the findings may have some agricultural applications, Mitchell-Olds says he is more interested in understanding natural variation and the evolutionary forces that have shaped that variation over thousands of years.

"We've been able to go to places where the environment is intact, where these genotypes have been sitting around for 3,000 years in the place where they evolved in the first place, and do science," Mitchell-Olds said. "This variation we see reflects history. We finally have the tools to find the genes and to understand their influence on physiology and fitness, and that's pretty cool."

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Story Source:

The above story is reprinted from materials provided by Duke University.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. K. V. S. K. Prasad, B.-H. Song, C. Olson-Manning, J. T. Anderson, C.-R. Lee, M. E. Schranz, A. J. Windsor, M. J. Clauss, A. J. Manzaneda, I. Naqvi, M. Reichelt, J. Gershenzon, S. G. Rupasinghe, M. A. Schuler, T. Mitchell-Olds. A Gain-of-Function Polymorphism Controlling Complex Traits and Fitness in Nature. Science, 2012; 337 (6098): 1081 DOI: 10.1126/science.1221636

Note: If no author is given, the source is cited instead.

Disclaimer: Views expressed in this article do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/top_science/~3/2MMf3eRb_IM/120830141335.htm

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US women to play Germany twice on 'victory tour'

Associated Press Sports

updated 12:16 p.m. ET Aug. 30, 2012

CHICAGO (AP) - The U.S. women's soccer team is going to savor its gold medal from the London Olympics a little longer.

The Americans said Thursday they will play two exhibitions against Germany next month as part of their post-Olympic "victory tour." The first game will be Oct. 20 in Bridgeview, Ill., with the second game three days later in East Hartford, Conn. The U.S. is 17-4-4 against the two-time World Cup champions, winning their last three meetings.

The Americans begin their tour Saturday against Costa Rica in Rochester, N.Y., Abby Wambach's hometown. They then host Australia on Sept. 16 in Carson, Calif., and Sept. 19 in Commerce City, Colo.

The U.S. women won their third straight Olympic title in London, beating Japan 2-1 in a rematch of last year's World Cup final.

? 2012 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.


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Should US men be worried?

PST: The U.S. men's soccer team has a few strikes against it heading into its World Cup qualifying match at Jamaica. Michael Bradley's injury is just the latest.

Red Bulls salvage tie with United

WASHINGTON (AP) - Wilman Conde scored in the 88th minute to lift the New York Red Bulls to a 2-2 draw against D.C. United on Wednesday night.

Source: http://nbcsports.msnbc.com/id/48844358/ns/sports-soccer/

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HBT: Phillies put struggling Worley on DL

UPDATE: After all that talk about how the bone chips weren?t hurting Worley?s performance the Phillies just announced that he?s headed to the disabled list and will undergo the surgery within the next 10 days. The lesson? Sometimes when something seems obvious it is, even when the people involved claim it isn?t.

==========

Once the season ends Vance Worley will have surgery to remove bone chips from his elbow, but in the meantime the Phillies right-hander is continuing to pitch through the discomfort. And his performance continues to be awful.

Worley failed to make it out of the fifth inning against the Mets last night and has now allowed 18 runs on 39 hits and 10 walks in 24 innings over his last five starts.

Yet afterward Worley insisted that the bone chips in his elbow aren?t to blame for his struggles, telling Jim Salisbury of CSNPhilly.com:

It hasn?t affected me. I?m just not getting pitches where I need to get them. It?s all about pitch location. That?s why I got beat tonight and pulled from the game.?I don?t feel anything at all. I?m just having a tough stretch.

So according to Worley it hasn?t had an impact on his performance, yet his performance has been really bad and the issue will require offseason surgery to fix. That?s a helluva coincidence.

Manager Charlie Manuel also told Salisbury that the team hasn?t considered shutting down Worley:

He tells me he?s fine and the trainers tell me he?s fine. That?s what I have to go by. We have the best doctors, supposedly, in the world. I go on what they tell me. He gets checked regularly. What he tells me, I?ve got to believe him.

Meanwhile, since July 1 he?s started 11 games with a 5.80 ERA and .350 opponents? batting average.

Source: http://hardballtalk.nbcsports.com/2012/08/29/vance-worley-keeps-pitching-poorly-keeps-saying-bone-chips-in-elbow-arent-to-blame/related/

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Wednesday, August 29, 2012

Brand Communications and Sponsorship Manager ? All jobs (page 1)

Brand Communications and Sponsorship Manager

Information:

Posted: 28 Aug 2012
Apply deadline: 26 Nov 2012
Location: Brazil
Company: bp

Job description:

This role has two main parts:
1) Regarding Brand Communications: this role is responsible for the coordination, implementation and performance delivery of all Castrol Above-The-Line, Digital and PR communications activity within Brazil. He/she is also responsible for supporting the development and execution of Point-of-Sale communications, Events and Promotions as per the needs determined with the Consumer Brands, Professional Brands and Trade Marketing areas. This should be achieved such that there is complete alignment with Castrol masterbrand and product brand guidelines and overall communications strategy, best practices are applied and agency selection and management is efficient and effective.?
2) Regarding Sponsorship: Castrol?s global and Brazil-specific sports and sponsorship assets have been identified as key marketing tools to achievement of the Brazil automotive business? aspirations over the five year period 2013-17. This role will be pivotal in mobilising the time and effort of the larger organisation behind leveraging sponsorship as a marketing tool within the Brazil business to deliver this objective. In particular, this role is responsible for the development and coordination of a complete, integrated consumer and customer strategy and program for the Brazil automotive business for leveraging the FIFA Confederation?s Cup 2013 and FIFA World Cup 2014.
Brand Communications:
? Oversee all Brazil creative development and production and manage all Brazil media activity in alignment with Regional and Global brand managers. This includes the development of annual media plans and execution management of all communications activity including social media and consumer/customer loyalty programs in line with agreed brand plans.?
? Develop annual communications plans with Ogilvy Media in conjunction with brand managers. Manage and coordinate the development of all communications planning and buying with Ogilvy Media.
? Manage communications development ? including creative development through production, following the outlined Global creative process. Manage and ensure creative and media tactics meet outlined business objectives.
? Oversee Sponsorship events and promotions, Digital and PR communications programs, ensuring connectivity with overall communication strategy. Oversee development of a strong digital marketing platform ? ensuring programs are innovative, effective and measure against strategic brand objectives.?

Sponsorships - General:
? Develop and periodically update a coherent and comprehensive sponsorship strategy for Castrol Brazil?s Automotive business that is aligned to the global sponsorship strategy and caters to the Brazil business? specific needs and its plans as per the 2013-2017 WILG strategy
? In coordination with Consumer Brands, Professional Brands and Trade Marketing managers, as well as Sales and GMU Sponsorship managers, manage the development of annual Brazil sponsorship plan for all Market Space brands, ensuring all sponsorship assets are fully leveraged, costs minimized and value is maximized.?

Sponsorships - Specific FIFA Confederations Cup 2013 (FCC) and FIFA World Cup 2014 (FWC):?
? Develop a world-class FCC and FWC 360? integrated sponsorship program for the Brazil business, and manage the implementation of the program with perfection helping drive a step-change in volumes and brand health for the business as per the Brazil WILG 2013-2017 plan.
? Differentiate the master brand from competitors using the platform of football
? Develop relationships with: a) other FIFA sponsors to optimize synergies and joint activation/ promotion/ PR / digital potential locally; b) relevant soccer media and act as both internal and external PR interface in alignment with local, regional and global guidelines, managing relevant third-party agencies accordingly

? University level education ? Bachelor?s degree; MBA or equivalent business school degree is desirable but not required.
? Tertiary qualifications in marketing or a related discipline are considered essential.
? 8+ years experience in Consumer marketing/advertising. FMCG marketing experience preferred. Experience working with sponsorships is highly desirable. Previous Channel Marketing and/or Sales experience would be advantageous.?
? Experience developing sponsorship-based marketing strategies highly desirable.
? Experience in developing customer/ consumer focused interactive digital media strategies highly desirable.?
? Experience in working in a global organisation, with understanding of processes and systems in which multinational companies operate.
? Strong impact and influencing skills
? High degree of personal impact
? Strong negotiations skills required
? Strong interpersonal skills
? Strong networking skills both within and outside the business unit
? Strong analytical/problem solving skills
? Strategic thinker, self-starter and team player
? Problem solver, ability to challenge status quo
? Strong leadership skills
No
Yes - up to 25%
No

Contact information:

Jobs: 1 ? 50 of 13274

Posted ? Title Location
22 Aug 2012 Free! Senior Project MetallurgistOrange NSW, Australia
15 Aug 2012 Free! Project Engineer?? Underground Tunneling ProjectColorado
15 Aug 2012 Free! Electrical Tech., Junior Mine Engineer, Senior Mine Engineer, Mine Geologist, Metallurgical Engineer, Mill Maintenance Mech., Mill Operation Tech., Mobile Maintenance Mech., Surface Mining operatorsElko, Nevada
15 Aug 2012 Free! Mine Staff AccountantElko, Nevada
15 Aug 2012 Free! Proposal Development SpecialistCalgary Canada
15 Aug 2012 Free! Senior Mining EngineerKoolyanobbing Operations, Australia
08 Aug 2012 Free! Tecnico Mantenimiento SintomaticoChile
08 Aug 2012 Free! T?cnico EletricistaBrazil
08 Aug 2012 Free! Technical Translator/?????????? ??????????? ??????????Magadan, Russia
08 Aug 2012 Free! Supervisor HR?ProjectMauritania
08 Aug 2012 Free! Welders and FabricatorsAbbotsford, BC
08 Aug 2012 Free! Superintendent (Water and Sewer Construction)Edmonton, Alberta
01 Aug 2012 Free! Analista FinanceiroBrazil
25 Jul 2012 Free! Geological ModelerBritish Columbia, Canada
18 Jul 2012 Free! Mine/Expl. GeologistElko, Nevada
18 Jul 2012 Free! Mine Production SupervisorsCory,Canada
27 Jun 2012 Free! Geotechnical EngineerAustralia
20 Jun 2012 Free! Mill OperartorsJerritt Canyon, Elko, Nevada
20 Jun 2012 Free! Staff AccountantElko, Nevada
20 Jun 2012 Free! Environmental Coordinator?? Needed ASAP!!!Northern Nevada?? at?a?Mine Site
13 Jun 2012 Free! General Manager?? RCI Electrical ServiceFort McMurray, AB
28 Aug 2012 Senior Administrative AssistantUnited States
28 Aug 2012 Operations Drilling SuperintendentUnited States
28 Aug 2012 Well Intervention EngineerUnited States
28 Aug 2012 Project Manager?? Liberty Rig Decommissioning ProjectUnited States
28 Aug 2012 Financial AnalystUnited States
28 Aug 2012 Upstream Internal Audit ManagerUnited States
28 Aug 2012 Upstream Internal AuditorUnited States
28 Aug 2012 Internal Auditor R&MUnited States
28 Aug 2012 Internal Audit Manager, ISTUnited States
28 Aug 2012 Senior Diving EngineerTrinidad and Tobago
28 Aug 2012 Process Safety EngineerUnited Kingdom/United States
28 Aug 2012 Product Control AnalystCanada
28 Aug 2012 Operating Management System SpecialistUnited States
28 Aug 2012 Gravity Drainage (GD) New Well Delivery Production EngineerUnited States
28 Aug 2012 International Federal Tax Audit Specialist (IRS & IDR?s)United States
28 Aug 2012 Specialist?? Reporting & AnalyticsMalaysia
28 Aug 2012 Performance Reporting LeadMalaysia
28 Aug 2012 Brand Communications and Sponsorship ManagerBrazil
28 Aug 2012 Channel Development Manager Open MarketBrazil
28 Aug 2012 Pricing and Competitor Intelligence ManagerBrazil
28 Aug 2012 Channel Development Manager IWS Co-Branded ProgramsBrazil
28 Aug 2012 Field TechnicianIndonesia
28 Aug 2012 Field Service Technician (Wellheads)United Kingdom
28 Aug 2012 Field Service EngineerUnited Kingdom
28 Aug 2012 Assembly & Test EngineerUnited Kingdom
28 Aug 2012 Subsea OperatorUnited Kingdom
28 Aug 2012 Senior Structural Engineer (For participants at?ECCS Job Fair, Lisbon)Norway
28 Aug 2012 Lead Structural Engineer (For participants at?ECCS Job Fair, Lisbon)Norway
28 Aug 2012 Graduate Piping EngineersNorway

?

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Frequently Asked Questions

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It doesn't matter how you type your keywords. For example, by typing ENGINEER and EngiNeer you will get the same search results.

How can I?find jobs that contain all of?the keywords?

Enter the specific keywords and select "ALL of the words" from 'Find results with' list.

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Source: http://www.miscojobs.com/jobs/job_580731.htm

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"Eden" to get North American release

LOS ANGELES (TheWrap.com) - The Toronto-based distributor Phase 4 Films has acquired all North American rights to director Megan Griffiths' drama "Eden," Phase 4 announced on Wednesday.

Griffiths and Richard B. Phillips Jr. wrote the screenplay for the project, and Jamie Chung, Beau Bridges and Matt O'Leary are set to star in the film, produced by Colin Harper Plank and Jacob Mosler.

The story follows a Korean-American teenager who is abducted and forced to work as a sex slave in Las Vegas after getting a ride home from a bar in New Mexico. Phase 4 is planning to release the film early in 2013.

"Eden" made its world premiere at the 2012 SXSW Film Conference and Festival, where it won several prizes. It also played at the 2012 Seattle International Film Festival, where Chung won the best actress award.

International sales for the film are being handled by the Los Angeles-based sales company Cinema Management Group (CMG).

CMG has already closed sales in a number of areas including Germany, Austria, Switzerland, Belgium, The Netherlands, Middle East, Japan and South Korea.

Source: http://news.yahoo.com/eden-north-american-release-215735494.html

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SAP ERP for your small business success | PReVent

Extend Technologies, part of the NTT DATA Group, designs, implements, and supports SAP solutions and services for medium to large organizations in both the public and private sectors enabling their customers to use innovative, value-adding, and proven deployments of SAP and complementary solutions to solve complex business challenges and thus transforming their companies. What they can do for you and your business is incredible and can help it grow tremendously.

Whether your company currently uses SAP as your strategic platform or is looking for advice on how to improve your SAP implementation you can depend on Extend. They can provide you with exactly the right balance between SAP technical services and consulting and you will end up with the best ERP solution that is custom made to your specific business requirements.

Extend Technologies? fantastic consulting team is at the center of their organization and are able to offer an end-to-end SAP experience. They maintain one of the widest services capabilities in the industry. They are able to provide SAP consulting capabilities such as HR/Payroll, SAP NetWeaver, Project Systems, Treasury, APO, Human Capital Management, and Financial & Management Accounting along with many others.

They also have Microsoft consulting capability which includes Microsoft .NET, SharePoint, Windows Mobile as well as Microsoft Integration to SAP. You?ll find that they also posses Enterprise change consulting capabilities such as Project Management, Change Management, Training, Business Process ?Best Practice? Design and IT Strategic Planning.

You can see how choosing Extend Technologies for your SAP ERP solution provider is one of the best business decisions you could make for your company whether you are interesting in extending your SAP integration beyond what is typically thought of as its boundaries or all of this is new to you.

Getting in contact with Extend Technologies could not be easier, they have numerous ways to contact them on their website so you can arrange for a consultation to find out preciously how they can help you and your business grow. They can help you achieve the results you want. Extend Technologies has the best SAP ERP Australia has to offer.

?

?

Source: http://prevent-ip.org/sap-erp-for-your-small-business-success/

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Tuesday, August 28, 2012

Mercedes-Benz Classic at the 2012 ... - The Automotive Press

Sorry, Readability was unable to parse this page for content.

Source: http://motoringdreams.blogspot.com/2012/08/mercedes-benz-classic-at-2012.html

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Link between protein and aggressive, recurring prostate cancer discovered

ScienceDaily (Aug. 27, 2012) ? In a study to decipher clues about how prostate cancer cells grow and become more aggressive, Johns Hopkins urologists have found that reduction of a specific protein is correlated with the aggressiveness of prostate cancer, acting as a red flag to indicate an increased risk of cancer recurrence.

Their findings are reported online in the Proceedings of the National Academy of Sciences on Aug. 27, 2012.

The team focused on a gene called SPARCL1, which appears to be critically important for cell migration during prostate development in the embryo and apparently becomes active again during cancer progression.Normally, both benign and malignant prostate cancer cells express high levels of SPARCL1, and reduce these levels when they want to migrate. The team correlated this reduction or "down regulation" of SPARCL1 with aggressiveness of prostate cancer.

"Our findings should allow physicians to not only pinpoint those patients whose cancers are destined to return after surgery, but could also reveal a potential new option for treatment," says Edward Schaeffer, M.D., Ph.D., an associate professor of urology, oncology and pathology at the Johns Hopkins University School of Medicine and co-director of the Johns Hopkins Prostate Cancer Multidisciplinary Clinic.

In their study, Schaeffer and lead investigator Paula Hurley, Ph.D., also found that SPARCL1 seems to play a role in predicting tumor recurrence in a number of other diseases including bladder, breast, colon, rectum, tongue, lung, skin and ovarian cancers.

The team is now working to decipher the specific mechanism that controls the gene in hopes of

developing a treatment that can reset SPARCL1 to normal levels and potentially prevent a patient's cancer from recurring. Hurley is currently investigating novel genes that are not only prognostic of lethal prostate cancer but also contribute to prostate cancer progression to metastasis.

According to the American Cancer Society, about 240,000 men in the United States are expected to be diagnosed with prostate cancer this year; the majority are over age 65.The disease is the second leading cause of death among U.S. men. An estimated 28,000 men in the U.S. will die of prostate cancer this year.

"While many of our patients are initially cured with surgery, some inexplicably have their cancers return," says Schaeffer. "We are working to identify patients at higher risk of recurrence and our ultimate goal is to develop new treatments that would prevent the return of the cancer."

Funding for the study was provided by the U.S. Department of Defense Prostate Cancer Research Program.Corresponding grant numbers are DOD-W81XWH-10-2-0056 and W81XWH-10-2-0046 PCRP Prostate Cancer Biorepository Network (PCBN).Additional support was provided by the Flight Attendant Medical Research Institute YSCA, the Patrick C. Walsh Prostate Cancer Fund at Johns Hopkins, the Howard Hughes Medical Institute Early Careers Physician Scientist Award, the American Urological Association Astellas Research Star Award, and the National Institute of Health, with corresponding grant number P3-0CA006973.

In addition to Schaeffer and lead investigator Hurley, other Johns Hopkins researchers involved in this study were Luigi Marchionni, M.D.; Brian Simons, D.V.M.; Ashley Ross, M.D., Ph.D.; Sarah Peskoe, Sc.M.; Rebecca Miller, B.S.; Zhenhua Huang, Ph.D.; Bora Gurel, M.D.; Ben Park, M.D., Ph.D.; and Elizabeth Platz, Sc.D., M.P.H.Other investigators included Nicholas Erho, M.Sc.; Ismael Vergera, Ph.D.; Mercedeh Ghadessi, M.Sc.; and Elai Davicioni, Ph.D., at GenomeDx Biosciences Inc., in Vancouver, Canada; as well as Robert Jenkins, M.D., Ph.D., at the Mayo Clinic in Rochester, Minn.; and David Berman, M.D., at Queens University in Kingston, Canada.

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Story Source:

The above story is reprinted from materials provided by Johns Hopkins Medicine.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. Paula J. Hurley, Luigi Marchionni, Brian W. Simons, Ashley E. Ross, Sarah B. Peskoe, Rebecca M. Miller, Nicholas Erho, Ismael A. Vergara, Mercedeh Ghadessi, Zhenhua Huang, Bora Gurel, Ben Ho Park, Elai Davicioni, Robert B. Jenkins, Elizabeth A. Platz, David M. Berman, and Edward M. Schaeffer. Secreted protein, acidic and rich in cysteine-like 1 (SPARCL1) is down regulated in aggressive prostate cancers and is prognostic for poor clinical outcome. Proceedings of the National Academy of Sciences, 2012; DOI: 10.1073/pnas.1203525109

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/most_popular/~3/SSLVIQ3-mqE/120827175935.htm

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Monday, August 27, 2012

Reshuffled Republican convention set to proceed on Tuesday

By Michael O'Brien, NBC News

TAMPA, Fla. -- Republicans will convene their convention on Tuesday, squeezing their canceled Monday programming into the span of three days.

Convention organizers seemed not to forsee any additional delays to the convention, though they said they would continue to monitor an impending hurricane.

The new schedule maintains the primetime schedule, with a lineup of Ann Romney and New Jersey Gov. Chris Christie speaking on Tuesday evening, former Secretary of State Condoleeza Rice, New Mexico Gov. Susana Martinez and vice presidential nominee Paul Ryan on Wednesday, and Florida Sen. Marco Rubio and Mitt Romney on Thursday.

Romney strategist Russ Schriefer wouldn't fully rule out the possibility, though, of adding a Friday session to the convention if inclement conditions force further postponement of convention activities.

"We are planning on Tuesday-Wednesday-Thursday," he said. "It's a hypothetical question"

Convention organizers argued that Monday's planned theme -- "We Can Do Better" -- could be weaved into the remaining three days of the convention as it's currently scheduled. Some speeches will be shortened to accommodate for the changes.

Republican National Committee Chairman Reince Priebus will call the convention to order on Monday, as had been planned, but will shortly thereafter gavel the convention into recess. Organizers called this a "very, very brief session -- probably no more than five minutes," and expressed doubts about whether many, if any, delegates would attend.

The roll call vote to formally nominate Romney for president is scheduled for Tuesday.

Source: http://firstread.nbcnews.com/_news/2012/08/26/13491748-reshuffled-republican-convention-set-to-proceed-on-tuesday?lite

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Small Business Marketing Update (Week 7) ? 5 Links to Small ...

weekly ledgerWell Howdy Do to all my small business pardners out there in the Wonderful Wacky Wild Wild Western Frontier-esque land of zee world wides webs! Welcome to the seventh installment of the Marketing Expertise?

So without further ado ? here are this week?s Top 5 Small Business Marketing Links:

1. 3 Small Business Marketing Tips for Getting Started On LinkedIn ? By Digital Marketing Consultant

LinkedIn is the most powerful purely business focused platform in the web 2.0 social media online space. Ever thought about how you could lasso this billy bucking of business marketing tool to boost your small biz marketing efforts? Maybe it?s time you did!

2.? Does Google+ Matter for Small Business Marketing? ? By Socialmouths

Not to be confused with Cotton Mouth, by compadres over at Socialmouths illustrate an excellent point about the marketing power and potential Google+ offers small businesses ? I mean it?s powered by Google after ? it stands to reason relevant searches will return at least a few posts by your business?right?

3.? Tips for companies without time for marketing ? by Amsterdam Press

No time for marketing? How can than be you bad boy ? don?t you know your business is likely to fail without it? Perhaps you can turn to your customers for a bit of ?crowdsourcing? help to promo your business!

4. The Business of Hollywood: 5 Marketing Lessons Entrepreneurs Can Learn from Film Studios ? By YFS Magazine

Did you think you weren?t big money enough to glom onto to a few Hollywood style marketing moves? Think again my pretties ? get a load of the Hollywood Prospectus.

5. Location-Based Social Media Marketing for Small Businesses ? By PC World

Smartphones, Foursquare, Facebook Location oh my! Locations based social media platforms bring the the customers a runnin? right to your front door. Tag ? you?re it!

Source: http://www.effectivemarketingmedia.com/2012/08/small-business-marketing-update-week-7-5-links-to-small-business-marketing-goodness/

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Sunday, August 26, 2012

Syria activists report 'massacre' by army near Damascus

AMMAN (Reuters) - The bodies of at least 200 people were found in a town close to Damascus on Saturday, according to activists who said most appeared to have been killed by Syrian troops "execution style".

The deaths would bring the toll from an offensive by President Bashar al-Assad's forces on Daraya, a working class Sunni Muslim town on the southwestern edge of Damascus, to 270, according to a tally by opposition activists in the capital.

Abu Kinan, an activist in Daraya, said most of the victims were found in houses and basements of buildings and had been shot by troops conducting house-to-house raids.

Due to restrictions on non-state media, it was impossible to independently verify the accounts.

"In the last hour, 122 bodies were discovered and it appears that two dozen died from sniper fire and the rest were summarily executed by gunshots from close range," Kinan said.

"Assad's army has committed a massacre in Daraya."

The Daraya Coordination Committee activists' group said in a statement that among those found with shots to the head were eight members of the al-Qassaa family: three children, their father and mother and three other relatives.

Their bodies were found in a residential building near Mussab bin Umeir mosque in Daraya, the group said.

Video released by activists showed numerous bodies of young men side-by-side at the Abu Suleiman al-Darani mosque in Daraya, many with what looked like gunshot wounds to the head and chest.

"A massacre," said the voice of the man who appeared to be taking the footage.

"You are seeing the revenge of Assad's forces from the people of Daraya: more than 150 bodies on the floor of this mosque."

Mohammad Hur, another activist in Daraya, said 36 bodies of young men were found in the morning in one building, along with several badly wounded people who could not be transferred to hospitals in the area because the army had occupied them.

"We are in the process of identifying the bodies and documenting how they died. Initial evidence shows that they were mostly shot at close range in the face, neck and head, execution style," Hur said by telephone.

"Female members from at least two families say that soldiers shot their brothers in front of them," he added.

The Syrian Observatory for Human Rights, which is based in Britain and headed by dissident Rami Abdelrahman, said it had received reports of dozens of bodies found in Daraya, but it had not yet ascertained how they were killed.

The army overran Daraya, one of a series of large, mostly run-down Sunni Muslim towns that surround Damascus, on Saturday after three days of heavy bombardment that killed 70 people, according to opposition sources and residents who said most of the dead were civilians.

The attack on Daraya was part of an army campaign to regain control of the outskirts of the capital, a mixture of built up areas and farmland where rebels had regrouped and relaunched guerrilla attacks on Assad's forces.

Assad belongs to Syria's minority Alawite sect, an offshoot of Shi'ite Islam that has dominated power in Syria for the last five decades. Members of the country's Sunni majority are at the forefront of the uprising.

(Reporting by Khaled Yacoub Oweis, Amman newsroom; Editing by Robin Pomeroy)

Source: http://news.yahoo.com/syria-activists-report-execution-style-killings-near-damascus-170333835.html

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How The 2 Most Excellent Music Programs For The Headset Weigh ...

If you love your radio then there are many sources that can provide quality sound through a quick and easy module. You can have your smart phones that have need designed in a way to accommodate a variety of applications that are good enough to serve your needs regarding quality sound. Pandora and slacker are two such mediums that can help you connect radio through internet.

You can access both of these applications from internet. They offered both free and paid services it?s only that their services are different. For free version, one would only access some few channels unlike paid services that one will be able to make a choice of the number of music he/she wanted to listen to.

Pandora standardizes on anybody?s? choice of streaming music. You can rely on this channel with respect to streaming quality. It allows one to create a station based on the most desired music collection. It performs better with Wi-Fi network using start phone with 3G services. The same happens with slacker, it works better with Wi-Fi network. This will also allow one to have the best of music. If you want to boost the performance then it will be good to buy wireless phone accessories.

Slacker allows one to personalize setting on how to access music. Just like Pandora, it allows one to create stations that they mostly desire and also assists one have a personal selection preset stations in different music genres. Even though most people think that using these applications is not easy to use, no, they are user friendly and it is only a matter of following instructions.
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If you think or consider with respect to users point of view then you can find them prioritizing slacker rather than Pandora. One can make his/her own setting so that he/she listens to music the way he/she desires. For example, if you love beats then slacker will allow you to have them with no problem. If one is into different genres, this is what they get form this application. But, one must never forget to buy smart phone accessories which ensure that one gets the best of quality sound. You should purchase different elements out of these accessories such as chargers, Bluetooth, microphone and other technological products.

Broadly speaking, you will get the best music out of slacker to entertain yourself. However, you should also consider that the cellular performance will vary from area to area. This is unlike Pandora that one can only access a standard music. All these amazing features can only be enjoyed if one can buy cell phone accessories.

Pandora implements limits for its users regarding requests for subscription. Some people choose twelve skips or six skips per hour. With free subscription, one can only get forty hours per month. Buy Alltel accessories and buy AT&T accessories to help maintain the look of your phone.

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Source: http://newtrendyoffersonline.com/cell-phone/how-the-2-most-excellent-music-programs-for-the-headset-weigh-against-each-other/

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Saturday, August 25, 2012

Learn how to Generate Leads Online Here | Label Muzik

One of the hardest parts of building an internet marketing or M.L.M business is lead generation and you ought to be mindful of that before you start. The majority of network marketers fail at this side of their business, but if you aren?t prepared to find out how to generate leads online effectively and efficiently, you?ll also join the large listing of disasters.

You have got to utilize a confirmed system to generate leads online which may also include certain other integral systems which should help you. Even though you do start out your business cold calling, you need a system for recording and tracking all of those calls, when you make the call, who you spoke to, the person?s e-mail address, and the prospect?s answer. After a month of writing everything down on bits of paper you?re going to finish up with a mass. Even if you only come away from that call with the prospect?s name and an email address that is a superb start. Building an e-mail list is the best way to start building a business.

Be very focused on who you contact. It may appear stupid, but if you?re talking to the wrong folks and attempting to promote a product that?s absolutely no use to them you are wasting everyone?s time. That time equals money, and if you spend a day cold calling all of the wrong folks it may be a pricey and fruitless exercise.

Come up with an original selling message after you have learned everything you potentially can about the product or service you?re promoting. Nobody has the time to listen to a heap of BS and they will quickly be in a position to smell that BS even down the phone! If you start off well and get into a debate with a prospect, if you are unable to answer one of his questions tell him so let him know you?ll get back to him later with the answer . Folk appreciate and respect honesty. The same principle applies if you generate leads online you should keep it real and keep the BS down to a minimum.

It?s easy to brand yourself and your product on the Internet but you need to get out there. Off-line there are some inexpensive ways of making yourself observable too. You might become a member of an association or a club where people in related businesses gather.

Online you can find the same kind of places where people gather ? social media sites like Facebook. This is an excellent spot to generate leads online. In Facebook there are countless thousands of Groups, join some Groups related to your product or business, discover what the group?s members are talking about and what issues they may be having and help. Don?t join a Group and start pitching your product immediately, show folks that you?re an expert and it won?t be long before they start asking you what you do. Don?t ever give anybody the belief that you are desperate to make a sale.

After you have built a relationship and made a sale request that person for a referral. This relationship has value to you and your client ; you have deciphered a difficulty for them so they will be happy to give you a referral if they can. The best referrals on the planet are ones from satisfied clients.

If you?re in the business of selling high end chrome wheels for dear vehicles, begin to know the people that sell those dear autos ? these kinds of relationships and networks can be very profitable and also bring the best leads.

Always refer people to your internet site and confirm it is kept up-to-date and is full of handy information for them. After you build your list you need to use an auto responder service to send out regular emails to your customers telling them about the newest news in your industry. Make it beneficial and full of information but don?t go on too long, and do not word it so it?s obvious you need to make a sale. You must get folks interested with a killer title and quickly lead them down to an action call, such as ?if you?d like more information? which should be at the end of your short email. If the recipient does click thru through that action call, you can be sure that this is a very qualified lead.

Understanding how to generate leads online isn?t rocket science you only need to learn the right techniques of going about it to be a successful network marketer.

Discover the resource that can help augment and speed up lead generation online. Let the Empower Network teach you how to exponentially grow your business in 90 days! Act Now!

Source: http://www.labelmuzik.com/business/learn-how-to-generate-leads-online-here

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FOR KIDS: Cool Jobs: Wild Science

Collecting data can be dangerous for scientists who work in the field

Web edition : Friday, August 24th, 2012

Discouraging polar bears from joining you for breakfast, avoiding hippos that might bite you in two and learning to bathe in caiman-infested rivers are not part of a scientist?s traditional job description. But if you?re a field researcher ? someone who gets out of the lab to collect and analyze data ? you may want to master some of these skills.

Visit the new?Science News for Kids?website?and read the full story:?Cool Jobs: Wild Science


Found in: Science News For Kids

Source: http://www.sciencenews.org/view/generic/id/343165/title/FOR_KIDS_Cool_Jobs_Wild_Science

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Vodou Haiti ? Blog Archive ? Just how a Taxi Photobooth Will Enrich ...

If you're new here, you may want to subscribe to Vodou Haiti RSS feed. Thanks for visiting!

The best way to cause to be able to web host an occasion will be to have a good time some thing distinctive in addition to stimulating. For the reason that have, you wish to ensure that your guests will be savoring everything you been employed so much generate. Undertaking is finding the situation to a target anytime intending the situation could be to suit ages young and old for a given time frame. Taxi photobooth tend to be the top billboards just for generating an entertaining feel for everyone alike and in addition they make the bare minimum magnitude of efforts on top of your conclude.

The best legitimate reason to create a taxi photobooth in the party is they basically spike your the enjoyment and then exhilaration. People normally de-stress should they be used in top on the camera system in a pleasurable surroundings, particularly if they have already props and additionally exciting apparel to enjoy having. A person?s party has already been the discuss with the city have you thought to liven this with small bit of innovation? Photobooths are the best way to consider the get together to another point and carry away outdoors sides of all your invitees, regardless of their age.

And also being this winner in the afternoon, colorings to help remedy your friends and family towards entertaining feelings which can be simple provide and best to bring home exactly the same day than to have a very good taxi photobooth. Naturally you should hire a qualified photo taker to take the pictures by start to finish, but why not even deliver your guests family home with the help of spur-of-the-moment thoughts on the outstanding night-time physical exercises received? Alternative you already know, you may wake to telephone calls via men and women that couldn?t cause it to, hoping that they been there mainly because of the prolonged thrill, results converse, and the best part, shots to demonstrate.

One of the benefits of owning a fabulous taxi photobooth for your celebration is how simple they?re just right from start to finish! Principals are not hard to undertake internet there are several sources of most spots. Photobooths variety any where from $500 so that you can One,400-500, according to product to select from, driving them to be easily affordable for every pockets. Also they are transferred, installed, and additionally categorised by business the place you acquired these guys because of. Moreover, a lot of companies may also deliver a staff registrant to activate together people, ensuring the best possible customer support.

Practically taxi photobooth enhance the excitement to your celebration, design wonderful products for your friends and family to look at house, and are also uncomplicated to get your day, furthermore, they please take a number of labor away from both together with wanting to think your invitees for all those several hours from the day. Immediately after walking around for hours on end to assure sufficient place photobooth taxi of all of the vendors, get ready to enjoy your personal time and energy.

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Source: http://vodouhaiti.org/?p=5887

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Friday, August 24, 2012

Game cam brings out the worst in local wildlife ? Living ? Bangor ...

FORT KENT, Maine ? Living out in the country, as we do here on Rusty Metal Farm, contact with some of the local wildlife is a near daily occurrence.

Sharing the farm with a seemingly endless variety of critters of all shapes and sizes with fur, feathers or scales means that on any given day the odds are in my favor of seeing something intriguing or mysterious enough to send me running to consult one of my nature books or the Internet.

But nowhere in my personal library or from within the depths of Google is there any reference to the animosity that bears hold toward photography.

Certainly, there are cultural and societal references documenting human emotions about being photographed.

In some cultures having one?s photo taken is perceived as having one?s soul stolen.

In others ? largely those populated by celebrities such as Sean Penn ? it?s an invitation to a smackdown.

Now you can add bears to the list of those who prefer to remain off camera.

Earlier this summer a friend and I set up a game camera next to Rusty Metal Pond in an attempt to capture images of a pair of beavers who had moved in and set up house.

Mr. and Mrs. Beaver were in the middle of constructing a pretty impressive lodge and we figured it would be fun to document their progress.

The camera itself is a fairly simple piece of technology running off a set of batteries and a built-in motion detector.

When an animal or bird ? or, as we learned, a bug, leaf or branch ? walks, flies or wafts past, the movement trips the camera?s shutter and a photo is taken. There?s even a flash for low light and night shots.

Patience, my friend told me, is the secret to getting good photos with a game camera. The longer it?s left alone, the better the odds of capturing something interesting.

What we were hoping for, of course, was a National Geographic-quality sequence of photos of our friends the beavers building their home.

What we got was a less-than impressive array of fuzzy night photos in which, if you squint and look at the images from the right angle, there may be a beaver doing something.

There also were several shots of the vegetation in front of the camera and way more photos than I ever needed of me on the riding lawn mower cutting the grass around the pond.

Were the beavers camera shy? Were their lodge-building techniques proprietary in nature and thus no photos allowed?

We may never know, but clearly if we wanted some game shots, a change of venue was in order.

So we reloaded the camera?s memory card and set off to position it on a trail here on the farm known to be frequented by creatures great and small.

And there it sat for more than two months ? out of sight and definitely out of mind until last week when it hit us, ?Wow, maybe we should go check the camera.?

A short hike later brought us to within sight of where we had left it, but it seemed to be missing.

Getting closer, we saw it was not missing, rather the tripod on which it sat had fallen over.

Getting closer still, we then saw it had not so much fallen as it had been smacked over and perhaps even stomped on.

What creature, we asked ourselves, would hold such malice toward an innocent game camera? We could hardly wait to get back home and find out.

The first series of photos showed the north end of a southbound female moose sauntering by either unaware of, or uncaring of the game camera, though now that I look back on it, her expression as she looked over her shoulder toward the lens may have been one of, ?Does this camera make my butt look big??

The next two shots were of a smaller moose at night and then some more of those fuzzy, ?find-the-animal-in-this-picture? shots.

Then ? pay dirt.

An extreme closeup of a black bear looking directly into the lens.

Now, we are not sure what happened next, but best as we can figure, bears ? or at least that particular bear ? are not exactly patrons of the visual arts.

The shot immediately after the close up is a sort of action photo as the camera is pushed to the ground.

The next series shows the ground from a profile angle since the camera was on its side with a bear apparently jumping up and down on top of it.

Bears are known for having a keen sense of smell, and my friend and I wondered if perhaps they have pretty good hearing to go with that and perhaps the soft ?clicking? of the camera?s shutter irritated the bruin.

According to the American Bear Association?s website, ?It is believed that black bears hear much better than humans, probably in the ultrasonic range.?

The structure of a bear?s ear is unique from other omnivores in that, according to the website: ?The middle ear consists of a balloon-shaped, bony structure that forms a resonating chamber around the ear drum.? Called the auditory bullae, this structure increases hearing sensitivity.

Over the years, I?ve had more than one bear encounter here on the farm ? from being charged by a mother bear with a cub, to having a young bear circle the small cabin I use as a writing studio.

Every time the bear and I have both come away unscathed ? if a bit rattled, at least on my part.

Bears seem to want to mind their own business and avoid humans.

Camera-toting paparazzi, on the other hand, could very well be fair game.

So, just in case, next time we set up the game camera, it?s going to be tied to a tree.

Julia Bayly of Fort Kent is an award-winning writer and photographer, who writes part time for Bangor Daily News. Her column appears here every other Friday. She can be reached at jbayly@bangordailynews.com.

Source: http://bangordailynews.com/2012/08/23/living/game-cam-brings-out-the-worst-in-local-wildlife/

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Tinley park mental health center - HEALTH, BEAUTY & FITNESS

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Ravens put on a show at Jaguars' expense

Baltimore Ravens quarterback Joe Flacco (5) high-fives wide receiver Torrey Smith (82) after Anquan Boldin, not pictured, scored a touchdown in the first half of an NFL preseason football game against the Jacksonville Jaguars in Baltimore, Thursday, Aug. 23, 2012. Ravens wide receiver Jacoby Jones (12) and center Matt Birk (77) jog off the field at right. (AP Photo/Nick Wass)

Baltimore Ravens quarterback Joe Flacco (5) high-fives wide receiver Torrey Smith (82) after Anquan Boldin, not pictured, scored a touchdown in the first half of an NFL preseason football game against the Jacksonville Jaguars in Baltimore, Thursday, Aug. 23, 2012. Ravens wide receiver Jacoby Jones (12) and center Matt Birk (77) jog off the field at right. (AP Photo/Nick Wass)

Baltimore Ravens wide receiver Torrey Smith, right, rushes past Jacksonville Jaguars defensive back Dwight Lowery in the second half of an NFL preseason football game in Baltimore, Thursday, Aug. 23, 2012. (AP Photo/Gail Burton)

Baltimore Ravens running back Vonta Leach, right, celebrates in front of Jacksonville Jaguars defensive tackle Terrance Knighton after scoring a touchdown in the second half of an NFL preseason football game in Baltimore, Thursday, Aug. 23, 2012. (AP Photo/Nick Wass)

Baltimore Ravens linebacker Jameel McClain (53) tackles Jacksonville Jaguars tight end Zach Miller in the first half of an NFL preseason football game in Baltimore, Thursday, Aug. 23, 2012. (AP Photo/Nick Wass)

Baltimore Ravens quarterback Joe Flacco (5) throws to a receiver as he is pressured by Jacksonville Jaguars defensive lineman C.J. Mosley (99), defensive end Andre Branch (90) and defensive lineman Jeremy Mincey in the first half of an NFL preseason football game in Baltimore, Thursday, Aug. 23, 2012. (AP Photo/Nick Wass)

(AP) ? The Baltimore Ravens probably wouldn't mind if the regular season began a week from Sunday.

The Jacksonville Jaguars, on the other hand, need all the time they can get before playing games that really count.

Joe Flacco passed for 266 yards and two touchdowns, and Baltimore received a strong performance from its defense in a 48-17 rout Thursday night.

Coming off a 27-12 defeat against the Detroit Lions, the Ravens were focused on scoring touchdowns instead of field goals and rectifying a defensive unit that was scorched for 507 yards.

They accomplished both goals with a solid showing against the previously unbeaten Jaguars.

"We're putting it all together now," Ravens cornerback Lardarius Webb said.

Same with the offense. Flacco completed 27 of 36 passes before leaving early in the third quarter. Most important, he put two touchdowns on the board instead of settling for field goals.

"If this was a regular-season game, we would have come out (feeling) pretty good about it," he said.

The Jaguars had very few feel-good moments in a humbling defeat that came on the heels of wins over the New York Giants and New Orleans.

"How we respond from this will be the test of this football team," coach Mike Mularkey said. "It's like being punched in the mouth. In all three phases, we just didn't give ourselves a chance to compete the way we did in the first two games."

Baltimore amassed 571 yards in total offense and had five drives of at least 80 yards. The 48 points were the most ever scored by the Ravens in a preseason game.

With support from a defense that kept Jacksonville quarterback Blaine Gabbert in check, the Ravens (No. 5 in the AP Pro32) built a 20-3 lead before Flacco took a seat.

Gabbert went 11 for 21 for 117 yards over three quarters, and Rashad Jennings, starting in place of holdout Maurice Jones-Drew, gained 57 yards on 13 carries.

"I'm not pleased at all in my game tonight. I left a lot of yards out on the football field," Jennings said.

Jennings wasn't the only Jacksonville player to express disappointment after the blowout.

"Maybe that is what we needed, to have that bad a feeling, even in a preseason game," Mularkey said. "This is why we play exhibition games. This will be a true test of this team to see how we bounce back from this. I am anxious to see how this team responds after getting pounded like we did. In all three phases, we didn't do the things we needed to do."

Jacksonville cornerback Rashean Mathis played for the first time this summer following knee surgery, but Jaguars cornerback Aaron Ross was forced from the game with an ankle injury and tight end Zach Miller left in the second quarter with an injured leg.

Fortunately, the Jaguars still have one preseason game left before the opener against Minnesota.

"You can't go into the season feeling the way we do now," Gabbert said. "This one leaves a nasty, nasty taste in your mouth. You never want to lose a game like this, even if it isn't the regular season."

Against the Giants and Saints, Gabbert drove the Jaguars (2-1) to a touchdown on their opening possession. In this one, Jacksonville started on its own 5 after a Ravens punt and made only one first down ? on a 16-yard completion to first-round draft pick Justin Blackmon ? before kicking the ball away.

Ray Rice began the subsequent drive with a 28-yard run, but the march stalled inside the 10 before rookie Justin Tucker kicked a 33-yard field goal. It was an unfulfilling score for the Ravens (2-1), who were intent upon improving their inability to get touchdowns when inside the 20.

That shortcoming would be resolved in Baltimore's third drive. Flacco went 8 for 9 for 87 yards and made it 10-0 with a touchdown throw to Anquan Boldin.

The march started with a 16-yard pass to Smith, who came up limping but returned later in the series and caught a key third-down pass. Smith missed last week's game with a sprained ankle.

Following another Jacksonville punt, Flacco went 5 for 5 on a 30-yard drive that ended with a 53-yard field goal by Tucker. In his effort to take the job from incumbent Billy Cundiff, Tucker has made all five of his field goal tries this preseason, including two from beyond 50 yards.

Gabbert finally got the Jaguars rolling late in the half, directing a 12-play, 73-yard march that produced a field goal with 56 seconds remaining.

On their first possession of the second half, the Ravens moved 80 yards to take a 20-3 lead. Flacco went 7 for 9 for 70 yards, completing passes of 7, 32 and 8 yards to Smith before concluding his night with a TD toss to Leach.

___

Online: http://bigstory.ap.org/NFL-Pro32 and http://twitter.com/AP_NFL

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/347875155d53465d95cec892aeb06419/Article_2012-08-24-FBN-Jaguars-Ravens/id-c3756cf12b154248bf54e4d10ae087af

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